NAUKA I KVAZINAUKA (izvorište inspiracije za mnoga SF dela) > EZOTERIJA

Poreklo vampira II

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S.:
hard core science - ko ne voli, neka ne cita dalje :) Ipak, sve je tu - i dnevna svetlost, i beli luk... jedino je krst malo problematican  :evil:

*****

"Stories of vampires date back thousands of years. Our modern concept stems from Bram Stoker's quirky classic Dracula and Hollywood's Bela Lugosi--the romantic, sexually charged, blood-sucking outcast with a fatal susceptibility to sunlight and an abhorrence of garlic and crosses. In contrast, vampires of folklore cut a pathetic figure and were also known as the undead. In searching for some underlying truth in vampire stories, researchers have speculated that the tales may have been inspired by real people who suffered from a rare blood disease, porphyria.

...

Porphyria is actually a collection of related diseases in which pigments called porphyrins accumulate in the skin, bones and teeth. Many porphyrins are benign in the dark but are transformed by sunlight into caustic, flesh-eating toxins. Without treatment, the worst forms of the disease (such as congenital erythropoietic porphyria) can be grotesque, ultimately exacting the kind of hideous disfigurement one might expect of the undead. The victims' ears and nose get eaten away. Their lips and gums erode to reveal red, fanglike teeth. Their skin acquires a patchwork of scars, dense pigmentation and deathly pale hues, reflecting underlying anemia. Because anemia can be treated with blood transfusions, some historians speculate that in the dark ages people with porphyria might have tried drinking blood as a folk remedy. Whatever the truth of this claim, those with congenital erythropoietic porphyria would certainly have learned not to venture outside during the day. They might have learned to avoid garlic, too, for some chemicals in garlic are thought to exacerbate the symptoms of the disease porphyria, turning a mild attack into an agonizing reaction.

...



PORPHYRINS all have in common a flat ring, mainly composed of carbon and nitrogen, and a central hole where a metal ion can sit. The basic ring (far left) becomes caustic when exposed to light;... Nontoxic examples include heme (a component of the oxygen transporter hemoglobin) and the chlorophyll that converts light to energy in plants.

*****

Hm, ne svidja mi se ova crvena boja, menjam.

DUNADAN:
ovo je odlichno!
pitam se kako su se provadjali albino jadnici tih davnih dana :)

poreklo vampira verovatno i vuche svoje korene u porfiriji ili slichnim poremecajima.
to bi objasnilo njihovu "pojavu" na geografski i kulturoloshki udaljenim podruchjima kao Juzna Amerika <=> Rusija
isto tako, lunarni ciklus na neke ljude deluje izuzetno snazno, shto bi opet objasnilo "pojavu" vukodlaka.
josh ako je zadrzao lanugo, embrionalne dlachice, u potpunosti je obrastao dlakama do kraja zivota.
mega :)
 :lol:

eric cartman:
:) Takve u Bosanskoj Krajini ubijaju kolcima  :)
Jel tako Dunadan? :!:

S.:

--- Quote from: "DUNADAN" ---
to bi objasnilo njihovu "pojavu" na geografski i kulturoloshki udaljenim podruchjima kao Juzna Amerika <=> Rusija
 
 :lol:
--- End quote ---


:) Verovatno, jos bi mozda i objasnilo nejednaku zastupljenost sirom globusa - pojedini genetski(?) poremecaji su ucestaliji kod nekih etnickih grupa. Sad je pitanje - da li su Sloveni podlozniji vampirizmu ili su bili posteniji i opisali sta su videli i to raspredali vekovima?

Ima jos jedan pasus koji moze da ti bude zanimljiv, vise je tehnicke prirode, skicira moguci mehanizam reakcije na svetlost:

"Porphyria arises because of a flaw in the body's heme-making machinery. The body produces heme and other porphyrins in a series of eight coordinated stages, each catalyzed by a separate enzyme. Iron is added at the end to make heme. In porphyria, one of the steps does not occur, leading to a backlog of the intermediate compounds produced earlier in the sequence. The body has not evolved to dispose of these intermediates efficiently, so it dumps them, often in the skin. The intermediates do not damage the skin directly, but many of them cause trouble indirectly. Metal-free porphyrins (as well as metalloporphyrins containing metals that do not interact with the porphyrin ring) can become excited when they absorb light at certain wavelengths; their electrons jump into higher-energy orbitals. The molecules can then transmit their excitation to other molecules having the right kind of bonds, especially oxygen, to produce reactive singlet oxygen and other highly reactive and destructive molecules known as free radicals. Metal-free porphyrins, in other words, are not the agents, but rather the brokers, of destruction. They catalyze the production of toxic forms of oxygen. "


Sta je jos ostalo? Vukodlaci, kao sto si rekla i sta jos?

DUNADAN:

--- Quote from: "S." ---
:) Verovatno, jos bi mozda i objasnilo nejednaku zastupljenost sirom globusa - pojedini genetski(?) poremecaji su ucestaliji kod nekih etnickih grupa. Sad je pitanje - da li su Sloveni podlozniji vampirizmu ili su bili posteniji i opisali sta su videli i to raspredali vekovima?

Ima jos jedan pasus koji moze da ti bude zanimljiv, vise je tehnicke prirode, skicira moguci mehanizam reakcije na svetlost:

"Porphyria arises because of a flaw in the body's heme-making machinery. The body produces heme and other porphyrins in a series of eight coordinated stages, each catalyzed by a separate enzyme. Iron is added at the end to make heme. In porphyria, one of the steps does not occur, leading to a backlog of the intermediate compounds produced earlier in the sequence. The body has not evolved to dispose of these intermediates efficiently, so it dumps them, often in the skin. The intermediates do not damage the skin directly, but many of them cause trouble indirectly. Metal-free porphyrins (as well as metalloporphyrins containing metals that do not interact with the porphyrin ring) can become excited when they absorb light at certain wavelengths; their electrons jump into higher-energy orbitals. The molecules can then transmit their excitation to other molecules having the right kind of bonds, especially oxygen, to produce reactive singlet oxygen and other highly reactive and destructive molecules known as free radicals. Metal-free porphyrins, in other words, are not the agents, but rather the brokers, of destruction. They catalyze the production of toxic forms of oxygen. "


Sta je jos ostalo? Vukodlaci, kao sto si rekla i sta jos?
--- End quote ---


pa pretpostavljam da je bilo koji poremecaj koji rezultuje i u odredjenim promenama fenotipskih karakteristika nosioca, dovodio do njegovog izopshtenja iz zajednice.
porfirija kao posledica mutacije bilo kog enzima koji uchestvuje u sintezi HEMa
albinizam kao posledica mutacije bilo kog enzima u enzimskim reakcijama sinteze melanina
zadrzavanje embrionalnih dlaka, shto sam vec pomenula

nocna aktivnost bolesnika sa porfirijom i razorno delovanje sunca u kombinaciji sa albinizmom lako moze da se ubaci u folklor i na kraju dobijesh vampira. :)

The molecules can then transmit their excitation to other molecules having the right kind of bonds, especially oxygen, to produce reactive singlet oxygen and other highly reactive and destructive molecules known as free radicals.

da
taj singletni kiseonik je mamara opasan.
moze da izazove mutacije chak i u zapakovanim delovima DNA.

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