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KIEL, Germany - In what was called an "ambitious" experiment,
a German man received a new jaw after surgeons grew a new
jaw bone in his back muscle and transplanted it to his mouth.
The man, who had his lower jaw cut out because of cancer,
was able to indulge in his first meal in nine years - a
bratwurst sandwich. Dr. Patrick Warnke, a reconstructive
facial surgeon at the University of Kiel, used 3D computed
tomography scanning and computer-aided design techniques to
produce a replacement for the jaw-bone defect. With that
data he created a titanium mesh cage that was filled with
bone mineral blocks and recombinant human bone morphogenetic
protein from the patient's bone marrow. The transplant was
implanted into the muscle below the patient's right shoulder
blade to grow, and seven weeks later the new bone graft was
transplanted as a free bone-muscle flap to replace the miss-
ing jaw bone. Four weeks after the procedure, the man was
able to enjoy a real meal.