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Gde bi trebalo lansirati sf ekspedicije

Started by PTY, 10-05-2012, 09:50:42

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Gaff

Sum, ergo cogito, ergo dubito.


PTY

A-ha!  8)






DNA used to encode a book and other digital information

















- A team of researchers in the US has successfully encoded a 5.27 megabit book using DNA microchips, and they then read the book using DNA sequencing. Their experiments show that DNA could be used for long-term storage of digital information.




http://phys.org/news/2012-08-dna-encode-digital.html#jCp

scallop

Never argue with stupid people, they will drag you down to their level and then beat you with experience. - Mark Twain.

PTY

Ljudi, ozbiljno vam kažem, to je - to.  :lol:

Mica Milovanovic

Mica

PTY

 :cry:


...eto, kad uporno obilaziš KSR i Egana...  :(

Mica Milovanovic

 :cry:


Evo mi ga Galileo's Dream pored ruke, ali je debeo... Kad da ga pročitam...
Mica

scallop

Lilit to sigurno može bolje od mene, ali ja to, onako seljački, vidim kao šifriranje. DNA se sastoji od samo 4 jedinjenja, adenin, guanin, citozin i timin koji su obeleženi, dva kao 0, a dva kao 1, binarni kod. Ako se DNA može sekvencirati, prepoznati, onda se može šifrirati. Problem je u čuvanju. Naravno, kad bi mi sve bilo jasno, ja bih sedeo tamo sa njima. :lol:
Never argue with stupid people, they will drag you down to their level and then beat you with experience. - Mark Twain.

Mica Milovanovic

To mi nije jasno. Kako to čuvaju...
Mica

scallop

Na niskim temperaturama, kao i mamutski DNA.
Never argue with stupid people, they will drag you down to their level and then beat you with experience. - Mark Twain.

mac

DNK se dobro drži i na telesnim temperaturama...

PTY

jessss, dna se strašno lepo drži na telesnim temperaturama.
kiborgizacija, gospodo, kiborgizacija... razmišljajte duž te linije.  :-| 

Mica Milovanovic

A kako, do đavola, uspevaju da "kaleme" aminokiseline u rasporedu koji im treba?
Mica

scallop

Blokovi nukleotida su kratki, piše na linku. I, mislim da se tekst podešava prema "rasporedu aminokiselina". DNA je šifra.
Never argue with stupid people, they will drag you down to their level and then beat you with experience. - Mark Twain.

zakk

Formirati nizove izgleda i jeste zeznuto, otud samo 96 segmenata po lancu. A čitaju ih lako, ta tehnologija je već prilično usavršena...
Why shouldn't things be largely absurd, futile, and transitory? They are so, and we are so, and they and we go very well together.

Mica Milovanovic

Čitanje nije problem. Tu sam prilično obavešten. Mi koji se bavimo istorijatom engleskog punokrvnog konja poslednjih nekoliko godina detaljno pratimo
šta se radi na ovom planu, pa čak i neki od nas (marginalno sam i ja uključen) pomažemo da se raščiste nedoumice zašto pojedine
"female families" engleskog punokrvnjaka nemaju iste sekvence MtDNA, kada bi, prema Stud Booku trebale da imaju zajedičkog potomka.


Ipak, nije mi jasno kako može da se tekst podešava prema rasporedu aminokiseline... Šta ti to znači da je DNA šifra?
Mica

scallop

Sećaš se kako su nekad izgledali šifarnici? Karton sa otvorima onoga šta se čita. DNA sekvence (koje su poznate) su taj karton.
Never argue with stupid people, they will drag you down to their level and then beat you with experience. - Mark Twain.

Mica Milovanovic

To sam i ja pomislio, ali vidi šta kaže:


Multiple copies of each block were synthesized
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[/size]
Mica

scallop

Ja do tog kamena, do tog bedema.


Dalje bih sigurno nešto zabrljao, pa bi me dohvatio neko ko bolje zna.
Never argue with stupid people, they will drag you down to their level and then beat you with experience. - Mark Twain.

Lord Kufer

Mogu oni sve da isprogramiraju, ali ne mogu da spreče fraktalni raspad sistema  8-)

Mica Milovanovic

Znam šta hoćeš da kažeš.


Ali što se tiče budućnosti korišćenja DNA za praktično skladištenje informacija, ne sumnjam da će naći načina da to urade...
Mica

Lord Kufer

http://www.icr.org/article/6927/

QuoteThe authors wrote, "The maximum likelihood time for accelerated growth was 5,115 years ago." Old-earth proponents now have a new challenge: to explain why—after millions of years of hardly any genetic variation among modern humans—human genomic diversity exploded only within the last five thousand years?

However, the same data conforms to and dramatically confirms biblical history. Since the author's date represents the maximum time, the actual DNA diversification event probably occurred even sooner. A biblical time scale indicates that a global flood occurred about 4,500 years ago, and this closely correlates with the time scale of the researcher's estimate.

The Bible clearly indicates that modern humans descended from Noah's three sons— Shem, Ham, and Japheth—and their wives. Such a dramatic reduction (bottleneck) in the overall size of the human population would certainly have been followed by a burst of genetic diversity, as it does in many animal populations.4 The genetic data from this research paper spectacularly confirms key biblical events and their Bible-based timelines
.

Naučnici (vlasti) hoće da dokažu da svaka ljudska osobina zavisi od gena, tj. da je uslovljavanje završeno još na tom nivou, a da posle samo treba dorađivati ispiranje mozga...

To bi oni hteli.


Lord Kufer

Razlog za eksploziju varijacija je ono što zovem Jerihonska manufaktura. Trebalo je proizvesti ljude kako bi se ostvario novi izum - država. To pada otprilike u to vreme. Da bi se proizveli ljudi trebalo je imati stabilan izvor hrane. Stočarstvo ali pre svega poljoprivreda... Posle toga tek ide Sumer i piramide, širom zemljine kugle.

Tehnologija zaista diktira skoro sve, a ona napreduje sve brže i brže. Ljudi uskoro neće biti ni potrebni. Robotizacija u pravom smislu reči je već počela.

Lord Kufer

Evo šta je sada počelo i to itekako objašnjava sav onaj outsourcing u Kinu, Indiju, Brazil itd.

http://www.proactiveinvestors.co.uk/columns/fullermoney-markets/10361/skilled-work-without-the-worker-fullermoney-10361.html

Skilled Work, Without the Worker

QuoteDRACHTEN, the Netherlands - At the Philips Electronics factory on the coast of China, hundreds of workers use their hands and specialized tools to assemble electric shavers. That is the old way.

At a sister factory here in the Dutch countryside, 128 robot arms do the same work with yoga-like flexibility. Video cameras guide them through feats well beyond the capability of the most dexterous human.

One robot arm endlessly forms three perfect bends in two connector wires and slips them into holes almost too small for the eye to see. The arms work so fast that they must be enclosed in glass cages to prevent the people supervising them from being injured. And they do it all without a coffee break - three shifts a day, 365 days a year.

All told, the factory here has several dozen workers per shift, about a tenth as many as the plant in the Chinese city of Zhuhai.

This is the future. A new wave of robots, far more adept than those now commonly used by automakers and other heavy manufacturers, are replacing workers around the world in both manufacturing and distribution. Factories like the one here in the Netherlands are a striking counterpoint to those used by Apple and other consumer electronics giants, which employ hundreds of thousands of low-skilled workers.

"With these machines, we can make any consumer device in the world," said Binne Visser, an electrical engineer who manages the Philips assembly line in Drachten.

Many industry executives and technology experts say Philips's approach is gaining ground on Apple's. Even as Foxconn, Apple's iPhone manufacturer, continues to build new plants and hire thousands of additional workers to make smartphones,
it plans to install more than a million robots within a few years to supplement its work force in China.

Foxconn has not disclosed how many workers will be displaced or when. But its chairman, Terry Gou, has publicly endorsed a growing use of robots. Speaking of his more than one million employees worldwide, he said in January, according to the official Xinhua news agency: "As human beings are also animals, to manage one million animals gives me a headache."

Mica Milovanovic

Kad smo već pomenuli KSR-a, upravo sam shvatio da je verzija Short, Sharp Shock-a objavljena u Monolitu 8 verzija iz Asimovsa, tj. nešto skraćena verzija u odnosu na onu koja je publikovana u ostalim izdanjima ove novele-kratkog romana...


Šteta. Verovatno je to bila jedina koju smo imali u tom trenutku... Ipak, to je bila 1993...
Mica

Lord Kufer

Ne mogu da se dosetim šta mu dođe KSR?
Kola za spavanje i ručavanje?

Nightflier

Sebarsko je da budu gladni.
First 666

PTY

Quote from: Mica Milovanovic on 23-08-2012, 00:44:09
Kad smo već pomenuli KSR-a,

... da dodam kako i on i Egan briljiraju u futurizmu bliske buducnosti i to zato sto retko ko u tvrdom sfu tako ozbiljno i pedantno ceprka po kontroverzama transhumanizma do Homo sapiens celestis.  :) 

Lord Kufer

Čitav članak je zanimljiv.

http://seedmagazine.com/content/article/the_body_politic/

QuoteAs soon as we are born, bacteria move in. They stake claims in our digestive and respiratory tracts, our teeth, our skin. They establish increasingly complex communities, like a forest that gradually takes over a clearing. By the time we're a few years old, these communities have matured, and we carry them with us, more or less, for our entire lives. Our bodies harbor 100 trillion bacterial cells, outnumbering our human cells 10 to one. It's easy to ignore this astonishing fact. Bacteria are tiny in comparison to human cells; they contribute just a few pounds to our weight and remain invisible to us.
It's also been easy for science to overlook their role in our bodies and our health. Researchers have largely concerned themselves with bacteria's negative role as pathogens: The devastating effects of a handful of infectious organisms have always seemed more urgent than what has been considered a benign and relatively unimportant relationship with "good" bacteria. In the intestine, the bacterial hub of the body that teems with trillions of microbes, they have traditionally been called "commensal" organisms — literally, eating at the same table. The moniker suggests that while we've known for decades that gut bacteria help digestion and prevent infections, they are little more than ever-present dinner guests.

But there's a growing consensus among scientists that the relationship between us and our microbes is much more of a two-way street. With new technologies that allow scientists to better identify and study the organisms that live in and on us, we've become aware that bacteria, though tiny, are powerful chemical factories that fundamentally affect how the human body functions. They are not simply random squatters, but organized communities that evolve with us and are passed down from generation to generation. Through research that has blurred the boundary between medical and environmental microbiology, we're beginning to understand that because the human body constitutes their environment, these microbial communities have been forced to adapt to changes in our diets, health, and lifestyle choices. Yet they, in turn, are also part of our environments, and our bodies have adapted to them. Our dinner guests, it seems, have shaped the very path of human evolution.

Lord Kufer

Naročito je ovo zanimljivo onima koji se zanimaju za genetiku  :twisted:

To find a biological answer to the question "Who are we?" we might look to the human genome. Certainly, when the Human Genome Project first produced a draft of the 3 billion-base-pair sequence, it was touted as a blueprint for human life. Less than a decade later, however, most experts recognize that our genomes capture only a part of who we are. Researchers have become aware, for example, of the influence of epigenetic phenomena — imprinting, maternal effects, and gene silencing, among others — in determining how genetic material is ultimately expressed. Now comes the notion that the genomes of microbes within us must also be considered. Our bodies are, after all, composites of human and bacterial cells, with microbes together contributing at least 1,000 times more genes to the whole. As we discover more and more roles that microbes play, it has become impossible to ignore the contribution of bacteria to the pool of genes we define as ourselves. Indeed, several scientists have begun to refer to the human body as a "superorganism" whose complexity extends far beyond what is encoded in a single genome.

zakk

Ohhohoho, sad si obradovao Scallopa, on voli svoje bakterije :)
Why shouldn't things be largely absurd, futile, and transitory? They are so, and we are so, and they and we go very well together.


scallop

Quote from: zakk on 23-08-2012, 15:00:59
Ohhohoho, sad si obradovao Scallopa, on voli svoje bakterije :)


I grinje. I grinje.


Kufer, pazi sad:


Nema materije bez bakterije,
nema roba bez mikroba.
Never argue with stupid people, they will drag you down to their level and then beat you with experience. - Mark Twain.

Nightflier

Quote from: LiBeat on 23-08-2012, 09:37:00
Quote from: Mica Milovanovic on 23-08-2012, 00:44:09
Kad smo već pomenuli KSR-a,

... da dodam kako i on i Egan briljiraju u futurizmu bliske buducnosti i to zato sto retko ko u tvrdom sfu tako ozbiljno i pedantno ceprka po kontroverzama transhumanizma do Homo sapiens celestis.  :) 


I Ber je tu dao svoj doprinos.
Sebarsko je da budu gladni.
First 666

PTY

Eh da, itekako jeste, i stvarno je greota što mu tako slabo poznajem opus... nekad je tako cvala ljubav između nas dvoje, tamo u doba Muzike krvi, pa stvarno ne znam šta nam se desilo.  :(

zakk

Dakle Scallope, oko onog našeg DNKisanja:

http://phys.org/news/2012-08-dna-encode-digital.html kaže
QuoteMultiple copies of each block were synthesized to help in error correction.

a http://www.wired.com/wiredscience/2012/08/dna-data-storage/
Quotean inkjet printer embeds short fragments of chemically synthesized DNA onto the surface of a tiny glass chip.

Dakle ne kodiraju tekst koristeći postojeće lance, niti prave pačvork od postojećih rezanaca, već ređaju nukleotide po želji.

Doduše niko da nam kaže KAKO.

Why shouldn't things be largely absurd, futile, and transitory? They are so, and we are so, and they and we go very well together.

Lord Kufer

Неће нам ни рећи.
Али, нама остаје нада да ће нам сваком по једну Милу Јововић, савршено биће... и тако то  8-)

Mica Milovanovic

QuoteDakle ne kodiraju tekst koristeći postojeće lance, niti prave pačvork od postojećih rezanaca, već ređaju nukleotide po želji.


Tako sam i ja razumeo, ali, pobogu, kako???
Mica

scallop

Ja rekoh dokle sam razumeo, a za posle da ne znam. U svakom slučaju, to lepljenje na tiny glass chips je mućo glass, pa sam sklon da poverujem da je to rađeno zbog kontrole šifriranja, a ne kao realan proces. Sve je to još Gibson rešio.
Never argue with stupid people, they will drag you down to their level and then beat you with experience. - Mark Twain.

zakk

http://www.guardian.co.uk/science/2012/aug/16/book-written-dna-code

QuoteWriting the data to DNA took several days.
...

The researchers, who have filed a provisional patent application covering the idea, used off-the-shelf components to demonstrate their technique.

To maximise the reliability of their method, and keep costs down, they avoided the need to create very long sequences of code – something that is much more expensive than creating lots of short chunks of DNA. The data was split into fragments that could be written very reliably, and was accompanied by an address book listing where to find each code section.

http://www.nature.com/news/dna-data-storage-breaks-records-1.11194

QuotePrevious attempts to store information in DNA have been held up by difficulties in making perfect long strands. Shorter molecules present less of a challenge, so Church and his colleagues kept their storage strands a mere 159 nucleotides long, and generated multiple copies of each to make catching and correcting mutations easier.

In each single strand, 96 nucleotides represented the encoded data as digital ones and zeroes; 19 nucleotides showed how these data blocks should be ordered; and 44 nucleotides enabled easier sequencing. The researchers' binary code assigned 'zero' to two types of nucleotide (As and Cs) and 'one' to the other two types (Gs and Ts).

A niko ne kaže kako, izgleda da je toliko očigledno svima da ne mora ni da se pominje :D

dakle: http://en.wikipedia.org/wiki/Gene_synthesis
Why shouldn't things be largely absurd, futile, and transitory? They are so, and we are so, and they and we go very well together.

Lord Kufer

Pa, RNK je u mozgu glavno sredstvo skladištenja informacije.

Nightflier

E, ja imam jedno pitanje. U vezi je sa temom, ali je uvod malo izokola.

Elem, onomad sam na FBu našao tekstić o trobojnim mačkama; tačnije, o trobojnim mačorima. Ako su trobojni, znači da imaju tri seta hromozoma - u tom konkretnom slučaju XXY - što ih čini neplodnim.

E sad - ispada da sam sve ove godine živeo u zabludi da živa bića mogu da imaju samo XX ili XY setove. Bi li neko bio ljubazan da me prosvetli?
Sebarsko je da budu gladni.
First 666

Mica Milovanovic

Jes vala, al za razliku od ovih DNA pisaca, sam(o) Bog zna moždanu tehniku pisanja...
Mica

Lord Kufer

Ima toliko šarenih životinja i biljaka. Nisam siguran da je to mnogo u vezi s hromozomima.

zakk

Quote from: Lord Kufer on 24-08-2012, 14:32:49
Pa, RNK je u mozgu glavno sredstvo skladištenja informacije.

DNK se retko koristi direkno za bilo šta, već se potrebno parče gena kopira na RNK pa onda RNK ide u organele i od njih se prave potrebni hormoni, proteini ili štaveć

Ali da se koristi za skladištenje informacija u smislu pamćenja, sećanja, VELIKO OROGMNO NE.
Why shouldn't things be largely absurd, futile, and transitory? They are so, and we are so, and they and we go very well together.

Lord Kufer

http://www.sciencedaily.com/releases/2010/04/100414134554.htm

QuoteOne fundamental property of the mammalian brain is that it continues to develop after birth, and one of the biggest drivers of the formation of new links between neurons is experience. Every time a baby sticks her finger on a pin or laughs in response to an adult's embellished gestures, a cascade of genetic activity is triggered in her brain that results in new, and perhaps even lifelong, synaptic connections.

self-renewal sistem

Mica Milovanovic

Zakče, može, al uz dosta pesničke slobode...  :)
Mica

Lord Kufer

http://www.sciencedaily.com/releases/2010/08/100810122035.htm

Human Cells Can Copy Not Only DNA, but Also RNA

"For the first time, we have evidence to support the hypothesis that human cells have the widespread ability to copy RNA as well as DNA," said co-author Bino John, Ph.D., assistant professor, Department of Computational and Systems Biology, Pitt School of Medicine. "These findings emphasize the complexity of human RNA populations and suggest the important role for single-molecule sequencing for accurate and comprehensive genetic profiling."

Jel to znači nešto kao "dinamička memorija" - pragmatično remodelovanje...

Recimo, zašto pesnik uvek piše nove pesme a ne stalno jednu te istu?