ZNAK SAGITE — više od fantastike — edicija, časopis, knjižara...

već smo ubili od tupljenja da gojaznost može imati veze s microbiomom, ali postoje i studije da izloženost nekim (patogenim) mikrobima (kao što su recimo infekcije hlamidijom (pneumoniae), citomegalo virusom ili hepatitsom A) može pozitivno/negativno korelirati sa gojaznošću.

Quote
Infections and obesity: A multinational epidemiological study
BJARNI THJODLEIFSSON1, ISLEIFUR OLAFSSON2, DAVI´D GISLASON1,
THORARINN GISLASON1, RAIN JO¨ GI3 & CHRISTER JANSON4
From the 1Medical Department and, 2Department of Clinical Chemistry, Landspitali University Hospital, Iceland, 3Tartu
University Lung Clinic, Estonia, and 4Respiratory Medicine and Allergology, Akademiska sjukhuset Uppsala, Sweden
Abstract
Viral infections have been associated with the aetiology of obesity in animal models. This study investigates the association
between 7 serological markers of infections and body mass index (BMI) in a population based sample. Individuals (n
985,
mean age 4297 (2855) y, mean BMI 25.594.2) from Iceland, Sweden and Estonia underwent a structured interview and
blood sampling. IgG antibodies were measured against Helicobacter pylori and the cagA protein, hepatitis A virus,
Toxoplasma gondii, herpes simplex virus 1, Chlamydia pneumoniae, Epstein-Barr virus and cytomegalovirus.
High-sensitive C-reactive protein (CRP) was measured as a marker of systemic inflammation. A significant positive
association between being overweight (BMI25 kg/m2) and IgG antibodies was found for Helicobacter pylori (OR 1.86, CI
1.342.60) and Chlamydia pneumoniae (OR 1.39, CI 1.031.88) and combined seropositivity had synergistic effect (OR
2.54 (1.623.97)). CRP was positively related to BMI (pB0.0001), whereas no significant association was found between
CRP and IgG antibodies against Helicobacter pylori and/or Chlamydia pneumoniae and CRP. The results suggest that
infections with Chlamydia pneumoniae and Helicobacter pylori are both significantly and synergistically associated with
overweight and this association is not related to indicators of systemic inflammation.

Quote from: Meho Krljic on 04-12-2016, 08:08:45
Nestlé says it can slash sugar in chocolate without changing taste  

Iako smanjuju ukupnu količinu šećera u proizvodima što je načelno ok, koliko sam shvatio, povećaće rastvorljivost šećera, što je možda  i lošije od prethodne verzije. Brža rastvorljivost znači da će se sva količina šećera u jednom još kraćem vremenskom intervalu nego pre naći u krvotoku, tj. moguće je da pik tog grafika koncentracije šećera bude možda još i veći nego pre (iako je površina ispod krive, tj. ukupna količina šećera smanjena i do 40%, kako navode). Veći skok koncentracije šećera znači i veći skok koncentracije insulina, odnosno veći "rebound" efekat, tj. veći osećaj gladi neko vreme nakon takvog obroka.

Quote from: Pizzobatto on 04-12-2016, 12:20:44
Eating ice cream for breakfast makes you more intelligent, Japanese scientist claims

http://www.independent.co.uk/life-style/health-and-families/health-news/ice-cream-breakfast-more-intelligent-japanese-scientist-yoshihiko-koga-smarter-clever-morning-a7434091.html

I rest my case

Korelacija bez objašnjene kauzalnosti najčešće je koincidencija, kao što je ovde slučaj. Ima bezbroj ovakvih primera, kao npr. broj gusara i prosečna temperatura. https://en.wikipedia.org/wiki/File%3aPiratesVsTemp%28en%29.svg


Vidi ovaj sajt sa ludim korelacijama:

https://www.google.com/url?hl=en&q=http://www.tylervigen.com/spurious-correlations&source=gmail&ust=1481474533077000&usg=AFQjCNG54vMHV-SDPCBxQJ-7G3_2bMfK_w

Mozgu je potreban sladoled, to je kauzalnost!

Ima smisla da se broj kupljenih japanskih auta poklapa s brojem samoubistava motornim vozilom, misim - kamikaze!

Misliš, vole ljudi da se osećaju udobno i kao svoji na svome u tim poslednjim trenucima. 

+ taj samurajski kod junačkog pozdrava s ovozemaljskim

Za samoubistvo najbolje je vozilo zemlje harakirija i kamikaza!

Inspirativno 

'Morbidly obese' woman drops 126 pounds and becomes fitness model

Odo ja na slavu, kaki manekeni ba!

broj unesenih kalorija irelevantan, insulin i kortizol se igraju. malo provokativno, al ima interesantnih detalja.
the book za punačke! (eufemizam )

evo epub:
https://www.dropbox.com/s/a7atm8g32igam9v/The%20Obesity%20Code.epub?dl=0

Kako da ne šećerim kafu, jelovaj lud!?!

Čitala sam sinoć u Zabavniku ovaj tekst, i definitivno je srušio sve u šta sam bila uverena, a u oblasti metabolizma:

http://politikin-zabavnik.rs/public/posts/paradoks-vezhbanja

Prženje mozga magnetom dovodi do promene ostatka tela:

http://newatlas.com/magnetic-brain-stimulation-alters-gut-bacteria/48755/

Može li magnetom s frižidera!

Will Doctors One Day Cure Obesity by Zapping Patients' Brains?

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What if the solution to obesity didn't have to involve difficult diets or dangerous surgeries? What if it could be as easy as putting on a helmet that zaps your brain just so? We're not there yet, but a new study in Italy shows how it may be possible and the surprising reason it could work.


The technical term for that brain zap is deep transcranial magnetic stimulation, or dTMS, a noninvasive technique that is currently being used to treat patients for depression and addiction. An electromagnetic coil in a helmet sends pulses to nerve cells to stimulate the release of neurotransmitters. In the case of addiction, the prefrontal cortex is the target of that stimulation, prompting the release of dopamine, the chemical that rewards us with pleasure. Livio Luzi, MD, a professor and head of endocrinology at the IRCCS Policlinico San Donato and the University of Milan, has been studying whether dTMS could be effective in treating obesity as an addiction to food. It worked in a way he and his team didn't quite expect.
"The treatment is quite short; it lasts five weeks and consists of 15 sessions, but what we are finding in our patients is that the effect [in the treatment group] is really long-lasting," Luzi told Yahoo Beauty. "After six months, and in some patients after 12 months, they are still eating less and losing weight."
That prompted Luzi to run a smaller study to see what might be extending the effect. This time researchers divided 14 clinically obese patients (three men and 11 women) ages 22-65 into two groups. One group received half-hour dTMS treatments three times a week for five weeks, while the other received a fake version of the treatment. After five weeks, the patients who had received dTMS had lost an average of 3 percent of their weight and 4 percent of their body fat, significantly more than the control group.
From several things measured in the patients, one big clue emerged: The fecal matter of the treated group showed that their gut microbiota contained more of the healthy bacteria associated with anti-inflammatory properties and a reduction of appetite. That means those zaps to the brain may have directly altered the subjects' gut microbiome.
Luzi cautions that this was a very small test group, and there are other possible hypotheses for the long-lasting weight loss. It's possible that after the initial weight loss from the dTMS, the subjects became more active because they had an easier time moving around. The stimulation may have also triggered a more permanent change in the subjects' neural connections — that other fascinating phenomenon called neuroplasticity. But so far, the evidence is strongest for what scientists like to call the "gut-brain axis."
Luzi is presenting these preliminary results at a meeting of the Endocrine Society in Orlando this Sunday. He and his team are applying for grants to run the experiment on a larger population.
With very few side effects (5 to 10 percent get a headache), dTMS could one day be a promising alternative to the invasive methods doctors currently use to treat obesity.

So možda nije tako loša, kaže jedna studija:


Eating Salt May Actually Help With Weight Loss, New Research Suggests

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A study has concluded that our fundamental knowledge of salt is apparently totally off base — and this news will make lovers of salty food quite hopeful.
According to an April 2017 study published in The Journal of Clinical Investigation, German scientists found that people who eat more salt are actually less thirsty than originally thought, although hungrier. They also discovered that the more salt mice consumed, the more calories they burned. In fact, these rodents needed to take in 25 percent more food just to maintain their weight.
Jens Titze, the lead author, has been studying this topic since 1991, when he was a medical student in Berlin, according to a report from the New York Times. This investigation eventually led to examining the effect a high-sodium diet had on crew members from a Russian space program, as well as mice.
So should salt be considered the newest weight loss food?
"It's hard to say based on limited data," Randy Wexler, M.D., an associate professor of family medicine at the Ohio State University Wexner Medical Center, tells Yahoo Beauty. "We do, at times, become surprised at what we thought we knew. However, this requires more evaluation to know if this is true."
Erin Palinski-Wade, author of Belly Fat Diet for Dummies, explains to Yahoo Beauty that according to the study findings, high sodium intake triggered an increasing production of glucocorticoid hormones to break down fat and muscle. "And this does require energy, so it would indicate that calorie expenditure may increase with a high sodium diet," she says. "However, increased appetite was also seen with elevated sodium intakes, so I would not recommend this strategy as a form of weight loss."
As for the currently understood role sodium plays in weight, Wexler states that at its most basic level, increased sodium causes water retention, which leads to weight gain. "However, in general, the body reaches a steady state or if the salt load was temporary, then the individual will go through diuresis [urinate more], and weight will usually return to baseline," he continues. "As for salt stimulating weight fluctuations through other mechanisms, it is conceivable but still not possible to say."
Palinski-Wade adds that further research may also conclude that high-sodium diets may not lead to weight gain. "Yet in real-life settings, diets rich in sodium are usually this way due to an increased intake of processed foods," she explains. "If you eat a diet high in sodium from fast foods, processed foods, excessive snacks, etc., you are most likely also taking in a diet rich in refined carbohydrates, saturated fats, and calories, which would cause weight gain regardless of your sodium intake."
Both experts also agree that salt regulation remains a complex issue.
"For example, we know salt also causes changes in cardiac function and the pliability of blood vessels in a manner separate from water retention, which can impact cardiac function," says Wexler. "Salt also plays a role in any number of body mechanisms, though it is not always clear. The bottom line is we are still learning much about salt and how it impacts the body, which can be said of many things about how the body works."
And Palinski-Wade points out that separate research suggests that some individuals are more sodium sensitive than others, which calls into question whether studies — such as this current one — apply to the general population or just a percentage of people.
"As a nutrition professional, my ultimate goal is to have my weight loss clients focus on a nutrient-rich diet filled with vegetables, fruits, fiber, and whole grains, along with lean proteins and plant-based fats," Palinski-Wade concludes. "Although sodium should be a focus, a well-rounded diet that is focused on whole foods over processed foods is, in my opinion, a more important focus."

https://youtu.be/j2nfm4A0R8E

Ne znam je li ovo postovano ranije, te prastajte ako jeste.

Interesantno, mada je

a) fokus Amerika

b) verovatno nece iznenaditi mnoge na ovom topiku

http://youtu.be/Y647tNm8nTI

Pitala sam se zasto ova deca iz dokumentarca ne gube kilazu iako navodno drze dijete i vezbaju (jedu tajno?) kad gle cuda...zapravo ne drze dijetu.

http://www.telegraph.co.uk/news/2017/07/12/household-dust-makes-people-fat-groundbreaking-research-indicates/?WT.mc_id=tmgoff_fb_tmg

da je tako, ja bih imao jedno trista kila. četristo kada mi žena ode u tazbinu

Kad neko kaze: ma, gojim se i od vazduha

Poenta: osoba koja je toliko lenja da neće ni prašinu da obriše po kući, mora biti debela. [emoji4]

 

Nema dosadnijeg kucnog posla, da budem iskrena!

Artificial Sweeteners Don't Help People Lose Weight, Review Finds

Large diet study suggests it's carbs, not fats, that are bad for your health

đed moga zeta doživio 90 godina, jeo samo slaninu sapunjaru, podmazivo arterije!

Normalno.



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inače, na američkom CBS-u rekli da novo istraživanje tvrdi jedno piće za žene i dva za muškarce dnevno jačaju srce i krvne sudove, napokon medicina ide u dobrom pravcu!

How the sugar industry tried to hide the health effects of its product 50 years ago

Diabetes is actually five separate diseases, research suggests

[emoji39]

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Jel' smo proradili?

Ovo je za detetov rođendan. Imali smo planove da proradimo u vakuumu dok ja ne proradim, čak i neke investicije u cilju unapređivanja, ali izgleda da ima više posla za mene nego što sam pretpostavljao, tako da su torte još uvek na ledu. Javiću ti ne brini.

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Divni su kapkejkovi!A što su na temi o gojaznosti?!

Pa ne mogu da ih stavim u "šta smo dobro krkali" kad ih nisam jeo [emoji16] A ovolika količina šećera i čokolade me asocira samo na jednu stvar [emoji1]
Ako ima tema o kolačima i slatkišima ubuduće ću tamo stavljati te đavolje rabote, nije mi palo na pamet da potražim.

E da, ovo su mafini, samo sa šlagom. Ne znam šta je kapkejk, jedino ako nije mafin sa šlagom...

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Pa otprilike to, mafin sa filom/šlagom  Ne znam, sad si me zamislio, meni ipak nekako ovo pogrešna tema za ove divotice 

Jelena kaže - kapkejk.

Jeste kapkejk, i savršeni su. Žena je majstorica, čarobnjak! Mad props!

Quote from: Meho Krljic on 20-01-2017, 06:49:55
Inspirativno 

'Morbidly obese' woman drops 126 pounds and becomes fitness model

volim tanke žene
i visoke

al one ne vole mene to je drugi par čorapa

Quote from: Гражданка Шульц on 01-08-2018, 17:24:21
Jeste kapkejk, i savršeni su. Žena je majstorica, čarobnjak! Mad props!

Ma da, nije što je moja ali razbija i sa ukusom i izgledom. Zato sam i prestao da žderem šećer, izgubilo je sportski karakter. 

Sad je trenutak da se citira Lilit: Petronije, ti si srećan čovek! 

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Tom Watson: how I lost seven stone and reversed my type 2 diabetes


Spojler: izbacio šećer i počeo da vežba.

A kobaje?

Quote from: Meho Krljic on 13-09-2018, 13:26:12
Tom Watson: how I lost seven stone and reversed my type 2 diabetes


Spojler: izbacio šećer i počeo da vežba.

Lepo je ovo, mada je naslov članka pomalo senzacionalistički, čak i zavaravajući. Dijabetes tipa 2 ne može da se preokrene, može da se utiče na njega dijetom i promenom načina života ali samo ukoliko pankreas još uvek ima očuvan dovoljan broj ćelija koje luče insulin. Ukoliko je ovaj broj pao ispod kritične tačke, tu ne pomaže ništa osim insulinske terapije. Na sreću, prvi simptomi dijabetesa tip2 praktično uvek nastaju usled toga što smanjen broj ćelija ne može da izadje na kraj sa povećanim faktorima rizika, ali još uvek postoji kritična masa beta ćelija Langerhansovih ostrvaca koje su dovoljne za normalno funkcionisanje organizma  i to samo u slučaju da se otklone svi glavni faktori rizika (debljina, sedeći način života, pušenje i nedostatak fizičkih aktivnosti, i naravno - stres koji je glavni okidač autoimunog procesa koji započinje razaranje samih ćelija). Dakle, dijabetes može da se preokrene ali samo ako se uoči u samom začetku i ukoliko se čovek pod hitno reši svih  faktora rizika. I posle toga ostaje pitanje daljeg propadanja ćelija u pankreasu, čiji mehanizam još nije potpuno objašnjen osim što se zna da je u pitanju autoimuni proces (zato je jelte i naveden stres kao glavni okidač).

Volim kad poneko zna.

 Everything You Know About Obesity Is Wrong

Pratim ovaj topik sa svojih 100 kila ali nisam baš oduševljen ovim člankom. Malo me smorio u prve dve trećine sa stigmatizacijom debelih osoba, da bi u poslednjoj trećini otkrio tajnu o gojaznosti koja i nije neka tajna, jer moderan način života i ishrane već dugo stoji kao broj jedan medju uzrocima gojaznosti. Koliko sam ukapirao naslov članka upućuje na beskorisnost dijeta koje se forsiraju a koje su potpuno jalove, i akcenat baca na jedenje ''dobre hrane'' umesto sveprisutne ''loše hrane'' kojom smo danas natrpani. Pošteno, ni to nije neka novost, ali me načisto iznenadio plot twist da su lekari glavni krivci za ovo stanje i da borba protiv gojaznosti treba da krene iz njihove ordinacije. Ako ćemo pošteno, borba treba da krene sa mnogo viših društvenih instanci, na nivou škola, vrtića, porodica, preventiva je ovde ključ. Kad čovek stigne do lekara on već ima konkretan problem koji lekar rešava (dijabetes, kardio, i sl.), a lekari ispadaju monstrumi jer nemaju razumevanja za njegovu gojaznost i njihov jedini savet je ''smršaj''. Onda u zadnjem delu teksta opet slušamo o stigmatizaciji debelih ljudi. Jedini koji su samo ovlaš ili uopšte nisu spomenuti u samom ovom tekstu su 1. država koja jedina može da pokrene preventivnu akciju na dovoljno širokom frontu i koja je jedina dovoljna jaka da se suporotsavi (druga stavka koja je samo ovlaš spomenuta) korporacijama koje se aktivno suprotstavljaju promeni načina života jer to direktno ugrožava njihove interese. Dakle, dve glavne stavke su poptuno omašene da bi se sva odgovornost svalila na pojedinca, u ovom slučaju lekare bez razumevanja i siledžije koji maltretiraju debele ljude. Nisam baš oduševljen...

Jedan link ne rešava ništa. Kad meni lekar napiše obesiti, pomislim: "Obesi se ti."

Da, pa ovo je pre svega pisano iz američke perspektive, pa je verovatno zato akcenat na lekarima, odnosno tematizuje se "epidemija" kao javnozdravstveni fenomen koji medicinska struka ne rešava adekvatno, iako je Berserker, naravno, u pravu, javno zdravlje nije usko interesovanje samo zdravstvenih profesionalaca. Dakle, tekst postoji u tom kontekstu kulture fat-shaminga u kojoj u SAD učestvuju i lekari u suviše velikoj meri itd.

Quote from: Berserker on 13-09-2018, 14:57:05

Quote from: Meho Krljic on 13-09-2018, 13:26:12
Tom Watson: how I lost seven stone and reversed my type 2 diabetes


Spojler: izbacio šećer i počeo da vežba.

Lepo je ovo, mada je naslov članka pomalo senzacionalistički, čak i zavaravajući. Dijabetes tipa 2 ne može da se preokrene, može da se utiče na njega dijetom i promenom načina života ali samo ukoliko pankreas još uvek ima očuvan dovoljan broj ćelija koje luče insulin. Ukoliko je ovaj broj pao ispod kritične tačke, tu ne pomaže ništa osim insulinske terapije. Na sreću, prvi simptomi dijabetesa tip2 praktično uvek nastaju usled toga što smanjen broj ćelija ne može da izadje na kraj sa povećanim faktorima rizika, ali još uvek postoji kritična masa beta ćelija Langerhansovih ostrvaca koje su dovoljne za normalno funkcionisanje organizma  i to samo u slučaju da se otklone svi glavni faktori rizika (debljina, sedeći način života, pušenje i nedostatak fizičkih aktivnosti, i naravno - stres koji je glavni okidač autoimunog procesa koji započinje razaranje samih ćelija). Dakle, dijabetes može da se preokrene ali samo ako se uoči u samom začetku i ukoliko se čovek pod hitno reši svih  faktora rizika. I posle toga ostaje pitanje daljeg propadanja ćelija u pankreasu, čiji mehanizam još nije potpuno objašnjen osim što se zna da je u pitanju autoimuni proces (zato je jelte i naveden stres kao glavni okidač).

što se tiče trenutne nauke, jedino je sigurno da je tip 1 autoimunski proces. autoantitela prisutna u krvi razaraju beta ćelije, a njihov smanjen broj ne luči dovoljno insulina.
kod tipa 2, radi se prvenstveno o otpornosti na insulin a ne o autoimunskom procesu uništavanja ćelija. preciznije: premda u startu insulina ima dovoljno, na beta ćelijama nema dovoljno insulinskih receptora, odnosno portala preko kojih insulin ulazi u ćeliju. što manje iskorišćenje, manja i dalja proizvodnja insulina i ulazi se u loop.
postoji i LADA dijabetes (mali procenat obolelih) koji je kombinacija tipa 1 i tipa 2.

receptori na beta ćelijama kod tipa 2 mogu da se stimulišu otklanjanjem svih faktora rizika koje si naveo. debljina jeste glavni faktor. ne zato što ne izgledamo lepo već što je debljina stanje konstantne inflamacije, a imunski sistem ima problem sa inflamacijom i želi da je ima samo kad mora da se bori protiv stranih patogena (mikroorganizama npr).